When sodium intake drops or you become dehydrated, your kidneys compensate by retaining lithium. This can cause lithium toxicity: tremors, confusion, nausea, seizures, and coma.
How it works
Lithium and sodium share the same renal reabsorption pathway. When sodium is depleted, kidneys increase lithium reabsorption.
What to do: Maintain consistent, adequate salt intake and stay well-hydrated. Do NOT go on a low-sodium diet without telling your psychiatrist. Monitor during hot weather or illness.
Source: FDA Lithium Prescribing Information; American Psychiatric Association Lithium Monitoring Guidelines
Disclaimer: Educational purposes only. Based on FDA drug labeling and NIH MedlinePlus. Consult your pharmacist or physician before changing your diet while on medication.
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