CYP3A4 inhibition by grapefruit reduces amlodipine metabolism, increasing drug exposure.
What to do: Limit or avoid grapefruit juice while taking amlodipine. Monitor for signs of low blood pressure (dizziness, lightheadedness).
Source: FDA Norvasc Prescribing Information
๐ง High-Sodium Foods (Processed Foods, Deli Meats, Canned Soups)⚡ Moderate
High sodium intake causes water retention and raises blood pressure, directly counteracting the blood pressure-lowering effect of amlodipine and other antihypertensives.
How it works
Sodium causes the kidneys to retain water, increasing blood volume and pressure.
What to do: Follow a low-sodium diet (less than 2,300mg/day). Avoid processed foods, canned soups, deli meats, and fast food.
Source: American Heart Association Dietary Sodium Guidelines; JNC 8 Hypertension Guidelines
Disclaimer: Educational purposes only. Based on FDA drug labeling and NIH MedlinePlus. Consult your pharmacist or physician before changing your diet while on medication.
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